

Bioinformatics and Statistical Genetics
- Date: 06/10/14
- Coordinator: Howard Brown
- Team: Jessica Smith, Tom Fisher, Sarah Branson, Ted Marks
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Introduction
Khartoum Winter School of Bioinformatics and Statistical Genetics is conducted since 2003.It was established by department of molecular biology – IEND. We conducted up to date 13 courses The facilitators and participants discuss approaches, means and domains of integrating disciplines for the study of target diseases and model organisms
Two branches are taught
Bioinformatics
Statistical Genetics
Bioinformatics
The courses introduce participants to the technical aspects of bioinformatics software and the development of bioinformatics software/approaches is included.
Bioinformatics Course Structure:
The course comprise a combination of lecture and hands-on tutorial-like sessions. The following topics are taught :
What is bioinformatics
Bioinformatics standards, programming, and open source developments
Internet/www in bioinformatics
Biological databases and data models
Sequence alignment pairwise, multiple aligment, searching BLAST, using clustalW and Bioedit programe
Primer design
Restriction mapping
Phylogenetic analysis
Structural Bioinformatics
Current topics in bioinformatics and future directions
Statistical genetics
This course is mainly focused on strategies for genetic mapping of human disease genes. The course is for researchers with little or no experience in using statistical genetic analysis programs. The goal of the course is to teach the participants both theory and application of methods for linkage disequilibrium and association studies analysis
Statistical genetics Course Structure:
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Aspects of Data collection
Creation of pedigree files
Introduction to Biostatistics
Calculation of Alleles and Genotype frequencies
Association analysis using TDT
Linkage disequilibrium analysis
Haploview program
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Structure
Arlequin